Acomplia

Acomplia (rimonabant) has not been licensed in the UK for smoking cessation. Whilst during clinical studies the drug clearly demonstrated a reduced craving for nicotine in patients the drug has only at the moment been approved as an obesity treatment. As this is a prescription medication we strongly advise that you seek to have a face to face consultation with your doctor in the first instance. Our service should not be interpreted as being a replacement to the treatment advice your doctor can provide.

Acomplia (rimonabant) Acomplia is a weight control drug released for sale on prescription in the UK on 21 st June 2006. It is available in 20mg tablets following a doctor reviewed OnlineClinic consultation.

How does Acomplia work?

Acomplia works on the so called endocannabinoid system, which is a system in the brain that affects energy balance, glucose and lipid metabolism and body weight. The result is that patients will experience the feeling of being full easier thus wanting to eat less than normally. This has been proven to significantly help obese patients achieve a weight loss if used in conjunction with a calorie reduced diet and exercise.

How much weight can be lost on Acomplia? Acomplia has undergone placebo-controlled studies involving a total of more then 6800 patients and the results were significant. The patients in phase 3 trials followed a diet prescribed by a dietician and they were advised to increase physical activity. Acomplia also reduced the risk of weight regain. A group of patients on Acomplia 20mg was re-randomized to Acomplia 20mg or Placebo after one year. The patients who continued on Acomplia 20mg achieved a total weight loss of 7.5kg over two years. The Patients who were transferred to placebo had a total weight loss of 3.1kg over the two years.

Patients treated with Acomplia also showed a significant reduction in waist circumference which is known to be an indication of intra-abdominal fat. The waist circumference, seen by experts as a more important measurement than the BMI, was reduced by 6-7cm.

Acomplia has been studied in approximately 2500 patients who suffered from obesity or overweight to study any side effects. The studies showed that 15.7% experienced side effects the most common being nausea, mood alteration with depressive symptoms, depressive disorders, anxiety and dizziness. Depressive disorders were reported in 10% people and suicidal thoughts in 1% of patients.

The following table shows all the adverse reactions from the four placebo-controlled clinical studies.

Undesirable effects

Contraindications Acomplia should be used with caution in patients with the following conditions: Moderate renal impairment Aged over 75 years Patients with epilepsy Patients using potent CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir, telithromycin, clarithromycin, nefazodone) Rare hereditary problems of galactose intolerance

Acomplia should not be used in patients with the following conditions:

• Severe renal impairment
• In patients with uncontrolled serious psychiatric illness such as a major depression
• Patients who had a cardiovascular event (myocardial infarction, stroke, etc.) less than 6 months ago
• Patients who are breastfeeding
• Patients who are pregnant
• Patients with depressive disorders and suicidal feelings
• Patients undergoing treatment for depression and taking antidepressants for it
• Patients with uncontrolled psychiatric illness other than depression
• Click here for a free medical consultation with a UK doctor to research treatment options - remember, it's free and without any obligation

If however the benefits of Acomplia re found to be more than its risk you can consult with the doctor and take it. Inform your family or relatives about the risk of taking Acomplia before you begin Acomplia treatment. Immediately discontinue taking Acomplia if symptoms of depression occur and seek medical help.

Indications for use

Acomplia is only licensed for weight control in patients with a BMI (Body Mass Index) above 30 or Patients with a BMI above 27 with associated risk factor(s), such as type 2 diabetes or dyslipidaemia.

Patients should take one 20mg tablet every morning with breakfast.

More information

If you wish to read more about Acomplia, including detailed information on contraindications and side effects, please click here.

How to buy Acomplia An OnlineClinic doctor following an online consultation can prescribe Acomplia. Simply fill in the online consultation form, which will then be reviewed by an OnlineClinic doctor. You will receive a personalised email diagnosis providing you with a link back to OnlineClinic from where you can buy Acomplia. Click here to proceed to the OnlineClinic consultation in order to buy Acomplia. Orders placed before 3pm Monday to Friday will be dispatched same day for next day delivery.

Acomplia (rimonabant) has not been licensed in the UK for smoking cessation. Whilst during clinical studies the drug clearly demonstrated a reduced craving for nicotine in patients the drug has only at the moment been approved as an obesity treatment. As this is a prescription medication we strongly advise that you seek to have a face to face consultation with your doctor in the first instance. Our service should not be interpreted as being a replacement to the treatment advice your doctor can provide.