History of viagra

Theoretically, with PDE 5 inhibited, coronary arteries would dilate and ease angina symptoms, and platelets would be less likely to stick to the surface of damaged arteries where they could trigger heart attacks.

Clinical studies on Sildenafil citrate as an angina treatment began in England in 1991. The first phase of the study showed no unusual findings and initial observations were promising.

However, as so often happens in scientific research, some unexpected findings arose. Of the males involved in the studies, many of them reported a marked increase in the tendency to get erections. The initial reaction from Pfizer's researchers was one of disappointment. Their focus was on angina and the erection issue was seen as a distraction. It was not until a full year later that the scientists were convinced that Sildenafil benefits to angina sufferers were modest at best, changed the direction of their study to focus on the compounds benefits to men suffering from erection problems. In late 1993, the first study on Sildenafil as a specific treatment for erection problems began in earnest. The results were so encouraging that a second study was conducted in 1994. By the time this study was completed, scientists had irrefutable data to show that a single dose of Viagra could promote erections in men who had previously been unable to sustain them.

Between 1994 and 1997, 21 clinical trials involving nearly 4500 sufferers of erection problems were conducted, at the end of which Pfizer filed a New Drug Application with the US Food and Drug Administration.

The FDA subsequently gave Viagra priority review status, which is reserved for drugs that represent major advances in treatment or fulfil a significant medical need.

In March of 1998, the FDA and the MCA of the UK, as the first oral medication for the treatment of erection problems, approved Viagra.

How Viagra works

This drug enables men with ED to respond to sexual stimulation. When a man is sexually aroused, the arteries in the penis relax and widen, allowing blood to flow into the penis which causes erection. As the arteries in the penis expand and harden, the veins that normally carry blood away from the penis become compressed, restricting the blood flow out of the penis. With more blood flowing in and less flowing out, the penis enlarges and one can maintain erection. When the sexual encounter is over, the erection goes away.

Being a responsible website “www.OnlineClinic.co.uk” encourage visitors to review all of the information available about Cialis before submitting a consultation form and to consider a full physical examination with a doctor to evaluate all possible causes for any medical problems. It is also recommended that do not use more than one type of impotence drug at the same time.

Viagra is one of the fastest selling drugs in today’s time. Designed with men in mind and produced to help them with any sexual problem they might encounter, history shows that the demand for Viagra has grown enormously over the last few years.

Since you know all about the history of Viagra, time has come for you to buy one and try one! Viagra – the first and the most popular, anti-impotence drug has created a mark in the history of treatment for erectile dysfunction. So why not get one and revive your sex life with fresh vigour. Viagra has changed millions of lives around the world. Now it is your chance to experience a positive change in your life.