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Evorel Sequi

Buy Evorel Sequi HRT patches in 50mcg in the UK

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Evorel Sequi is a hormone replacement therapy (HRT) treatment in the form of patches applied directly to your skin to effectively alleviate many symptoms associated with the menopause. Evorel Sequi is a pack for contains both Evorel and Evorel Conti that can be used to alleviate symptoms, encourage a regular monthly bleed and reduce the possibility of side effects that absorbing both oestrogen and progestogen continuously can trigger for some women.

To buy any prescription medication in the UK including Evorel Sequi, you must complete a quick consultation. Once approved, this HRT treatment is available from OnlineClinic in a 12-week (three-month) supply consisting of 24 patches.

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Order in the next 8h and 36min to receive your order Friday, 28th October

How to buy Evorel Sequi online?

Evorel Sequi is a combination of two Evorel patches; Evorel that contains just synthetic oestrogen and Evorel Conti that contains synthetic oestrogen and progestogen. There are equal numbers of Evorel and Evorel Conti in each pack, and at OnlineClinic, you can buy a three-month (12-week) supply. When taken alternatively, Evorel Sequi can reduce many menopausal symptoms such as hot flushes, vaginal dryness, night sweats and mood swings. Evorel Sequi are patches that can be stuck onto a smooth area of your skin – for example, the buttocks, back or waist – with the hormones being absorbed into the bloodstream. For many women, they find the low maintenance nature to be preferable over the daily tablet option.

Buying Evorel Sequi online is simple and requires a quick consultation. This is mandatory for every prescription medication in the UK, whether it's a face-to-face appointment or ordered online. At OnlineClinic, this takes just a few minutes and when ordered before 4.30pm, you will receive your medication the very next day.

What is Evorel Sequi?

The hormone replacement therapy (HRT) pack that offers both Evorel and Evorel Conti, Evorel Sequi allows you to control the hormone release by alternating the patch usage following doctor recommendation. Applied onto the skin as a patch, the hormones absorbed through your skin, which can have many benefits. One being the low maintenance nature as Evorel patches are only applied twice a week, compared to HRT tablets that need to be remembered daily. For those women who also prefer not to ingest tablets, or experience side effects when doing so, may find HRT patches to be more suitable.

Using this method effectively, you can alleviate many symptoms associated with the menopause and post-menopause as well:

  • Night sweats
  • Hot flushes
  • Vaginal itching
  • Vaginal dryness
  • Mood swings
  • Irregular periods

These HRT treatments can also aid bone mass density that have decreased due to the drop in hormones, and can be used to treat osteoporosis.

At OnlineClinic, you can buy a 24-patch set of Evorel Conti and Evorel to last three months.

Why combine two Evorel patches?

By alternating patches, your body isn't continually fed hormones and this follows your existing cycle more closely. By taking the patches at the first time in the right order, you avoid the additional increase of progestogen.

Short facts about Evorel Sequi
How to use

One Evorel patch is applied at a time. Start with 2 Evorel patch for 14 days before swapping to Evorel Conti for the next 14 days. Evorel Sequi is always a 28-day cycle.

How it works

Evorel contains just oestrogen whilst Evorel contains oestrogen and progestogen. Both patches works in the same way by absorbing through the skin to help alleviate menopausal symptoms.


Evorel Sequi is highly effective when used correctly. Proven to reduce hot flushes, night sweats, mood swings and vaginal itching/dryness, Evorel Sequi can also be used to treat osteoporosis.


Dosages of Evorel Sequi vary depending on the patch. Evorel patches contain 50mcg of estradiol. Evorel Conti patches contain 50mcg of estradiol and 170mcg of norethisterone.

Side effects

Side effects of Evorel Sequi are unlikely but can include headaches, trouble sleeping, weight gain and mood changes.

How does Evorel Sequi work?

Evorel Sequi works by each patch being placed a clean, dry area of skin and synthetic hormones absorbing through the skin. This helps to alleviate many discomforting symptoms caused by the menopause. The active ingredient in Evorel Sequi depends on the type of patch. The Evorel Conti patch contains a combination of oestrogen (estradiol) and progestogen (norethisterone), whilst Evorel contains just estradiol.

Evorel Sequi contains four Evorel patches and four Evorel Conti patches that are worn in a cycle (detailed in the below section) to help increase the amount of female sex hormones in your system that you will have lost during the menopause.

By swapping between the Conti and Evorel patches, your body doesn't have a continual flow of progestogen hormones, however still a level, which is known to improve the health of your womb and reduce the risk of developing endometrial cancer.

How to use Evorel Sequi?

Evorel Sequi is called so as it use din a sequence (in this case, a cycle of 28 days). Using Evorel Sequi is simple and requires alternating the different patches for maximum effectiveness:

  • For the first 14 days, use the Evorel patch
  • This should be changed twice a week (for example, Monday and Thursday)
  • For the next 15-28 days, change to one Evorel Conti patch at a time
  • Again, this should be changed twice a week

Due to change twice a week, in a 28-day cycle, you should use four Evorel patches and four Evorel Conti patches.

Where to place the patch

  • The buttocks are a popular location, as is the waist area or thighs
  • Make sure it is a smooth area where the patch isn't going to rub off or irritate
  • Apply any new patch to a different area than the last position
  • Do not apply to broken skin
  • Patches are waterproof and appropriate for swimming, exercising and washing

How to apply the patch

  • Clean and dry your skin before application
  • Don't use creams or lotions on the selected area
  • Patches should be changed twice a week, conveniently spaced out (on the Wednesday and a Sunday for example)
  • There isn't a break between patches. Continue to use HRT for as long as you please
  • Periodic doctor's appointments are advised to monitor your progress

If you forget to change the Evorel patch, or if the patch falls off, just reapply or apply a new patch as soon as you remember and continue to change the patch on the chosen day.


The dosages of Evorel Sequi depend on whether it is an Evorel patch or Evorel Conti patch. Evorel patches contain 50mcg of synthetic oestrogen (estradiol) whilst Evorel Conti contains both synthetic oestrogen (estradiol) and progestogen (norethisterone) with dosages of 50mcg and 170mcg respectively.

Side effects and precautions

Another benefit of Evorel patches is that they are extremely well tolerable for the vast majority of women. This is due to the hormones being absorbed into the skin through the patch, rather than you ingesting orally. If you do experience side effects, this tends to be controllable and temporary, and can include headaches, trouble sleeping, weight gain and mood changes. The full list of side effects is included in the patient leaflet attached at the bottom of this page, and if they are unmanageable, you can visit your doctor to discuss alternative options.

There are precautions to take into account before buying Evorel Sequi. These include if you are, have or have had:

  • High blood pressure
  • High cholesterol
  • Diabetes
  • Endometriosis
  • Obese
  • Epilepsy
  • Deep vein thrombosis
  • Heart failure heart attacks or strokes
  • Increased risk of blood clots
  • A hysterectomy
  • Asthma
  • Depression
  • Breast cancer or oestrogen-sensitive cancer
  • Allergies to any of the ingredients

These are all included in the patient leaflet and will be detailed by your doctor either through a face-to-face appointment or online consultation.

Treatment Information

Treatment Information
Product Name: Evorel Sequi
Active Ingredient(s): Estradiol and Norethisterone Acetate
Manufacturer: Janssen Cilag
Administration: Topical
Presentation: Patches
Available Dosage: 50 mcg
Exemption: Subject to medical prescription
Application: Women over 18 looking to relieve the symptoms of menopause
Posology: Apply relevant patch below the waist 2 times per week
Description: Evorel Sequi is a form of hormone replacement that provides relief from the symptoms of menopause
Drug class: HRT, sequential combined
Alcohol consumption: No known influence
When breastfeeding: Caution is recommended, ask your doctor and read the leaflet thoroughly for each treatment
When pregnant: Not recommended, ask your doctor for alternatives
Download Evorel Sequi - Patient Information Leaflet
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